an:03936339
Zbl 0584.62180
Barlow, William E.
General relative risk models in stratified epidemiologic studies
EN
J. R. Stat. Soc., Ser. C 34, 246-257 (1985).
00150828
1985
j
62P10
Cox regression; multiplicative models; exponential additive models; relative risk; stratified epidemiologic studies; Parameter estimates; matched case-control design; large prospective study; synthetic retrospective study
Multiplicative, additive, and exponential additive models of the relative risk in stratified epidemiologic studies are considered. Parameter estimates of the additive model are shown to have poor statistical properties and an alternative is suggested. This model is generalized to allow each predictor in the model to have either a multiplicative or additive effect on the relative risk.
Two examples are presented. One is a standard matched case-control design and the second is a large prospective study analysed as a synthetic retrospective study. All models may be fitted by making slight changes in existing software.