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Measuring synchronization in the epileptic brain: a comparison of different approaches. (English) Zbl 1135.92310

Summary: We investigate the relative merit of different linear and nonlinear synchronization measures for characterization of the spatio-temporal dynamics of the epileptic process. Analyzing long-lasting multichannel electroencephalographic recordings from more than 20 epilepsy patients, we show that all measures are able to identify brain regions of pathological synchronization associated with epilepsy, even during the seizure-free interval, and are able to detect a long-lasting transitional preseizure state. These findings render synchronization measures attractive for future prospective studies on seizure prediction.

MSC:

92C50 Medical applications (general)
92C20 Neural biology
92C55 Biomedical imaging and signal processing
62M10 Time series, auto-correlation, regression, etc. in statistics (GARCH)
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[1] DOI: 10.1016/j.eplepsyres.2005.12.004 · doi:10.1016/j.eplepsyres.2005.12.004
[2] DOI: 10.1109/TBME.2005.847541 · doi:10.1109/TBME.2005.847541
[3] DOI: 10.1016/S0167-2789(99)00140-2 · Zbl 0976.92011 · doi:10.1016/S0167-2789(99)00140-2
[4] DOI: 10.1103/PhysRevLett.88.174102 · doi:10.1103/PhysRevLett.88.174102
[5] Boashash B., Time-Frequency Signal Analysis: Methods and Applications (1992)
[6] DOI: 10.1007/s004220050540 · Zbl 0928.92014 · doi:10.1007/s004220050540
[7] DOI: 10.1097/00004691-200105000-00002 · doi:10.1097/00004691-200105000-00002
[8] DOI: 10.1097/00004691-200105000-00001 · doi:10.1097/00004691-200105000-00001
[9] DOI: 10.1209/epl/i2004-10173-x · doi:10.1209/epl/i2004-10173-x
[10] DOI: 10.1016/S0167-2789(00)00087-7 · Zbl 0962.92020 · doi:10.1016/S0167-2789(00)00087-7
[11] DOI: 10.1103/PhysRevE.67.021912 · doi:10.1103/PhysRevE.67.021912
[12] DOI: 10.1016/j.clinph.2004.08.025 · doi:10.1016/j.clinph.2004.08.025
[13] DOI: 10.1017/CBO9780511755743 · doi:10.1017/CBO9780511755743
[14] DOI: 10.1103/PhysRevE.65.041903 · doi:10.1103/PhysRevE.65.041903
[15] DOI: 10.1063/1.1938487 · doi:10.1063/1.1938487
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