×

zbMATH — the first resource for mathematics

Computer analysis of structurization processes of nucleic acids. (Russian. English summary) Zbl 1457.92131
Summary: The long-term experience of mathematical modeling complex cosmological systems (star systems, protoplanets cloud) has allowed organizing researches of structurization processes of macromolecules of ribonucleic acids. Essentially new in our approach the modeling not only structurization as separate phenomenon, but process of macromolecule birth as a whole is. The results of research of structurization processes of RNA macromolecules are represented. The application of multiprocessor computer complexes has allowed to carry out a series of calculations for much longer molecules RNA – ferments, which length exceeds some hundreds nucleotides. The received results not only confirm a hypothesis about intermittence of process of lengthening of a molecular circuit but also allow making an estimation of the period of this process.

MSC:
92D20 Protein sequences, DNA sequences
92-10 Mathematical modeling or simulation for problems pertaining to biology
PDF BibTeX XML Cite
Full Text: DOI MNR
References:
[1] Eneyev, T. M.; Kozlov, N. N.; Kugushev, E. I., Preprint No. 69, Processes of structurization of biomolecules. Results of mathematical modeling (1995), Moscow: Keldysh Institute of Applied Mathematics, Russian Academy of Sciences, Moscow
[2] Kozlov, N. N.; Kugushev, E. I.; Eneyev, T. M., Structure-forming characteristics of transcription process, Mat. Model., 10, 6, 3-19 (1998)
[3] Kozlov, N. N.; Kugushev, E. I.; Eneyev, T. M., Parallel calculations by solving some problems of astrophysics and molecular biology, Mat. Model., 12, 7, 65-70 (2000)
[4] Kugushev, E. I.; Starostin, E. L.; Pirogova, E. E., Mathematical model of the formation of three-dimensional structure of RNA (1997), Moscow: Keldysh Institute of Applied Mathematics, Russian Academy of Sciences, Moscow
[5] Kim, SH; Suddath, FL; Qugley, GJ; McPherson, A.; Sussman, JL; Wang, AHJ; Seeman, NC; Rich, A., Three-Dimensional Tertiary Structure of Yeast Phenylalanine Transfer RNA, Science, 185, 4140, 435-440 (1974)
[6] Lee, S-Y; Zuker, M., J. Biomol. Struct. Dyn., 8, 5, 1027-1044 (1991)
[7] Sprinzl, M.; Dank, N.; Nock, S.; Schon, A., Compilation of TRNA Sequnces and Sequences of TRNA Genes, Nucleic Acids Res. Suppl., 19, 2127-2171 (1991)
[8] Benham, C. J., Geometry and Mechanics of DNA Superhelicity, Biopolymers, 22, 11, 2477-2495 (1983)
This reference list is based on information provided by the publisher or from digital mathematics libraries. Its items are heuristically matched to zbMATH identifiers and may contain data conversion errors. It attempts to reflect the references listed in the original paper as accurately as possible without claiming the completeness or perfect precision of the matching.