Fitt, A. D. Flow in the canal of Schlemm and its influence on primary open angle glaucoma. (English) Zbl 1308.76344 Bonilla, Luis L. (ed.) et al., Progress in industrial mathematics at ECMI 2006. Papers of the 14th European conference of the European Consortium for Mathematics in Industry, Leganés, Madrid, Spain, July 10–14, 2006. Berlin: Springer (ISBN 978-3-540-71991-5/hbk). Mathematics in Industry 12, 843-847 (2008). Summary: Primary Open Angle Glaucoma (POAG) is a major cause of blindness, affecting 65-70 million sufferers worldwide ([ERC04]). The eye produces aqueous humour (AH: a water-like substance secreted by the ciliary body) which flows behind the iris, through the pupil aperture, out into the anterior chamber (AC) and drains from the eye via the drainage angle. From the drainage angle the AH passes through a biological filter (the trabecular meshwork or TM) into the canal of Schlemm (SC), the main drainage route from the eye, and finally exhausts into “collector channels”. POAG occurs when this drainage mechanism is somehow compromised [FW92]. Essentially the AH cannot be removed quickly enough and as a result the intraocular pressure (IOP) increases in the eye. Contrary to popular belief, glaucoma and elevated IOP are not synonymous. Though very often associated with elevated IOP, glaucoma is, in reality, an optic nerve neuropathy. Notwithstanding this, elevated IOP is always regarded as potentially harmful to the eye. In the current study we therefore seek to model the flow of AH from the AC through the TM and into the SC and to couple this flow to predictions of changes in IOP.For the entire collection see [Zbl 1124.00010]. MSC: 76Z05 Physiological flows 92C50 Medical applications (general) PDFBibTeX XMLCite \textit{A. D. Fitt}, Math. Ind. 12, 843--847 (2008; Zbl 1308.76344) Full Text: DOI