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The role of a transient potassium current in a bursting neuron model. (English) Zbl 0810.92002
Summary: Presented here is a biophysical cell model which can exhibit low- frequency repetitive activity and bursting behavior. The model is developed from previous models [the author et al., Biol. Cybern. 65, 487- 500 (1991); ibid. 69, 87-94 (1993)] for excitability, oscillations and bursting. A stepwise development of the present model shows the contribution of a transient potassium current \((I_ A)\) to the overall dynamics. By changing a limited set of model parameters one can describe different firing patterns; oscillations with frequencies ranging from 2- 200 Hz and a wide range of bursting behaviors in terms of the durations of bursting and quiescence, peak firing frequency and rate of change of the firing frequency.

MSC:
92C20 Neural biology
92C05 Biophysics
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